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Adept Therapeutics Inc.
Beverly, Massachusetts, United States
2 days ago

Description

We are seeking highly organized, collaborative and self-motivated Scientist or Associate Scientist or Research Associate to join us harnessing various modalities of antibody therapeutics to modulate novel and challenging therapeutic targets in Immuno-Oncology. The successful candidate will be responsible for wet lab work for the discovery of antibody therapeutics from early discovery up to pre-IND stage. The successful candidate will utilize molecular biology and immunology knowledge and skills to help discover and develop innovative antibody therapeutics to fulfill unmet medical needs for cancer patients. The successful candidate should be flexible, ready to troubleshoot, and have excellent communication and teamwork skill to ensure smooth co-ordination and completion of assigned tasks and activities. Full training will be provided.

We sponsor H-1 visa application and offer global business travel and working opportunity. 

If interested, please send your resume to jobs@adepttx.com

KEY RESPONSIBILITIES 

  • Perform molecular, cellular and immunological experiments, including but not limited to PCR, electrophoresis, plasmid construction, western blot, protein engineering, protein expression and purification, cell culture of cell lines, transient and stable transfection, isolation, phenotyping and culture of human, monkey and/or rodent primary cells.
  • Learn and optimize company platform technology, including but not limited to high-throughput single B cell cloning/culture, 96-well transfection, production /purification and quantification of antibodies/biologics; commitment to simultaneously handle 4-8 96-well and/or 24-well plates is required.
  • QC of purified proteins using standard techniques, such as SDS-PAGE and SEC-HPLC.
  • Characterization of antibodies (transfection supernatant or purified) by employing flow cytometry, ELISA, ADCC, CDC, ADCP, and/or other biochemical or cell-based functional assay(s).
  • Timely document and maintain detailed experimental laboratory notebooks; generate and analyze appropriately high-quality experimental results for the preparation presentation for internal/external use.
  • Draft and/or review technical reports/research protocols/SOPs, and scientific manuscript for patent application and/or publication.
  • Support external collaborations, including CROs and academic laboratories.
  • Work at a fast pace and adapt to changing priorities to meet program and team needs.
  • Such other responsibilities as may be assigned from time to time.


Requirements

QUALIFICATIONS 

  • Ph.D. or M.S. or B.S. in molecular biology, cell biology, immunology, biochemistry, biomedical engineering.
  • Ph.D. with 2+ years or M.S. with 4+ years or B.S. with 5+ years of academia or industry working experience.
  • Proficient in molecular biology and/or basic immunobiology skills, including PCR, DNA and protein electrophoresis, molecular cloning, culture of primary cells and cell lines, transient/stable transfection and cell line generation, flow cytometry, ELISA.
  • Experience of antibody discovery, GPCR overexpressing cell line generation, or cell-based potency assay, or animal immunization, and/or in vivo studies is a plus.
  • Track record of demonstrating analytical skills, bench skills and problem-solving skills.
  • Must be a team player and collaborator in a fast-growing environment.
  • Excellent verbal and written communication and interpersonal skills.
  • Position title and compensation will be determined by years of relevant experiences.

BENEFITS

  • Bonus Pay
  • Employee Incentive Plan: Stock Option
  • Health Insurance Benefit
  • Retirement Plan: 401(K) or Roth 401(K), 401(K) Matching
  • Paid Time Off: Vacation, Sick day, Personal day
  • Flexible Work Schedule

COMPANY BACKGORUND

Adept Therapeutics Inc. (AdeptTx) is an innovative start-up biotech company located at Woburn and Beverly in Great Boston area, MA, with passion for following the science and committing to find potentially life-changing medicines for people with unmet medical needs. Focusing on T cells, Natural Killer (NK)cells and immune-suppressive myeloid cells, we leverage multiple advanced antibody technologies to discover fully human or humanized antibody therapeutics to enhance anti-tumor immunity. We are establishing and optimizing two unique platforms including immune cell engager bispecific antibodies and multi-functional tri-specific antibodies, which change tumor microenvironment (TME) to boost immune responses against cancer cells through 1) recruiting and activating effector immune cells and 2) modulating immune-suppressive TME to support tumor killing effector cell function. Our expertise in GPCR antibody discovery and development enables us to reach for the “high-hanging fruits”, the most challenging targets for therapeutic antibody discovery. Our broad product portfolio focuses on both hematological malignancies, such as cutaneous lymphoma, and solid tumors including triple negative breast cancer, ovarian, colon, kidney, renal and pancreatic cancers etc.

Adept Therapeutics, Inc. is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, national origin, marital, domestic partnership or civil union status, age, disability, genetic information, status as a veteran or as a member of the military or status in any group protected by applicable federal or state laws.

Job Information

  • Job ID: 58810600
  • Location:
    Beverly, Massachusetts, United States
  • Position Title: Scientist / Associate Scientist / Research Associate
  • Company Name: Adept Therapeutics Inc.
  • Job Function: Pre-Clinical,
    Research
  • Job Type: Full-Time
  • Job Duration: Indefinite
  • Min Education: BA/BS/Undergraduate
  • Min Experience: 5-7 Years
  • Required Travel: 0-10%
  • Salary: $55,000.00 - $120,000.00 (Yearly Salary)

Please refer to the company's website or job descriptions to learn more about them.

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